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Immuno-modulatory effect of Turmeric (Curcuma longa) and Aloe Vera on cultured Polymorphonuclear cells (PMN) and adherent mononuclear cells

Complementary and alternative therapeutic measures off-late have gained significance because they have been shown to be clinically efficient with minimal side effects compared to mainstream treatments. Plant medicines are far and away safer, gentler and better for human health than synthetic drugs and with much less side effects. Aloe vera and Curcuma longa are two of such plants, which have been proven to have medicinal properties by several groups of researchers. However, the exact effect of these extracts on
cultured human adherent and non-adherent cells is still controversial. Very few studies have been done in this regard. Adherent and non-adherent cells in humans form a very important component of immune system. Studying the effect of Aloe vera and Curcuma longa on these cells, can go a long way in understanding the immuno-modulatory effects of these plants. In this study, we tested the immuno-modulatory effects of mannan from Aloe Vera and Curcumin from turmeric rhizome using human cells (PBMC). We used cell culture and Bradford's protein estimation methods and determined that mannan inhibits the proliferative response in human PBMCs, whereas Curcumin has a proliferative response towards human PBMCs.

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http://www.webmedcentral.com/article_view/5113

The value of wet cupping as a therapy in modern medicine - An Islamic Perspective

Cupping is a tradittional concept thought to help in medical conditions and has become increasingly more popular in certain environments. We present a review on cupping with its potential applications in modern medicine with a focus on the Islamic perspective of this technique.

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http://www.webmedcentral.com/article_view/4785

What are the Effects of Topical N-Acetylcarnosine [eye drops] on Cataract-Inhibited Vision in an Elderly Subject? - A Case Report

Introduction: Cataract onset has a limited prognosis presenting a diagnostic and therapeutic challenge. Mild cataract-inhibited vision is typically managed by Doctors of Optometry with prescription eyeglasses to manage clouding of the lens or glare. If cataracts progress, surgical correction may be recommended.Case: A 72-year-old male presented with mild R>L cataract-inhibited vision requiring prescription eyeglasses. This patient was simultaneously examined in two separate eyewear clinics (by Doctors of Optometry) both before and after the patient self-administered 90-days solution N-Acetylcarnosine eye drops. At follow up, this patient's vision was so improved that both Optometrists concluded that new eyeglass prescriptions with lower lens strengths were necessary.Conclusion: The effects of N-Acetylcarnosine eye-drops in this subject may be associated with reducing the prescription-strength of his eyeglasses.

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http://www.webmedcentral.com/article_view/3214

Ubiquinone Increases Performance of an Elderly Runner: A Case Report

Manufacturers of Coenzyme Q10 present different reports in marketing Ubiquinol or Ubiquinone. Each one suggests that their product is more favorable for resolving compromised health issues or poor energy metabolism associated with aging. This case study reports the running performance of a 71-year male runner while taking Ubiquinol, or Ubiquinone, each for 90-days, or taking neither supplement following a 14-day washout period. The subject's best performance time on the same course while taking Ubiquinone was 2.28% faster than his time on the same course after a 14-day washout period without supplement dose. The subject's best performance time on the same course while taking Ubiquinol was –1.16% slower than his time on the same course after a 14-day washout period without supplement dose. The results from a single-subject Case Report are definitively inconclusive, and thus call for more research by collecting dose-aided and dose-fasted timed performances from a larger contingent of male and female runners of all ages.

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http://www.webmedcentral.com/article_view/2596

Exaggerated Autonomic Asymmetry: A Clue to Nutrient Deficiency Dysautonomia

Seventeen adult Caucasian subjects were diagnosed clinically with dysautonomia, based on symptoms. Sixteen had asymmetrically different blood pressures measured simultaneously in both arms. Fourteen admitted to craving for sweets, salt or reactions to ingestion of sugar. Of these, 9 had abnormal erythrocyte transketolase changes indicating loss of thiamine homeostasis. Beriberi is the prototype for functional dysautonomia in its early stages.  It is hypothesized that excessive ingestion of simple carbohydrates results in defective oxidative metabolism in autonomic nervous system control mechanisms, resulting in exaggeration of normal asymmetric reflex action, an effect similar to that induced by mild chronic hypoxia. Abnormal thiamine homeostasis and dysautonomia have been reported in a number of degenerative brain diseases.
Running title:
Nutrient deficiency dysautonomia with asymmetric brachial pulse pressures

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http://www.webmedcentral.com/article_view/1854

Menopausal Symptom Management With Acupuncture For Women With Breast Cancer

Background: Hormone therapy is often used for menopausal symptoms, yet non hormonal interventions are the focus when treating menopausal symptoms induced by chemotherapy. A significant need exists for menopausal symptom relief for women following treatment for breast cancer. Objective: To test acupuncture for menopausal symptom relief for women following treatment for breast cancer as well as changes in ovarian hormones and quality of life.Setting: The study was conducted through the Yale University. Data were collected in the General Clinical Research Center at Yale.Methods/Design: Randomized, placebo-controlled, clinical trial study.Participants: 39 women experiencing hot flashes following treatment for breast cancer were assigned to one of three groups: Specific Acupuncture (n=16), Non Specific Acupuncture (n=17), or Enhanced Usual Care (n=6). Intervention: The experimental treatment consisted of specific acupuncture points related to menopausal symptoms. The placebo treatment in this study consisted of acupuncture at points identified as irrelevant to the symptoms of menopause. The control group received educational materials related to symptom management and healthy life activities.Primary Outcome Measures: Hot flash frequency over time, quality of life, and ovarian hormone levels.Results: Both acupuncture groups demonstrated a reduced average number of hot flashes; the control group did not show a reduction in hot flashes. The Specific Acupuncture group experienced an average of three hot flashes fewer per day at study end, compared to the control group. There was no significant difference in average quality of life scores across the three groups. The average difference in ovarian hormone measurements across time was not different (p=0.542).Conclusion: All women in the study experienced reduction in hot flash frequency with greater reduction in the acupuncture groups, suggesting participants benefited from study membership. It may be that symptom monitoring by daily symptom recording impacts symptom perception in a positive way.

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http://www.webmedcentral.com/article_view/1544

Sleep Disruptions and Hot Flashes in Post Menopausal Women with Breast Cancer

Purpose:The purpose of this secondary analysis was to explore the associations between the frequency of hot flashes and sleep disruptions experienced by post menopausal women with the diagnosis of breast cancer and received acupuncture treatments for hot flashes.Data Sources: Data were gathered for this secondary analysis from 47 African-American, Hispanic, and Caucasian women experiencing hot flashes after receiving treatment for breast cancer who were enrolled in an intervention study of acupuncture for menopausal hot flash reduction.Conclusions:Strong correlations were found between sleep disruptions, total hot flashes, daytime hot flashes, and night sweats at the conclusion of treatment and over the entire 12 weeks of follow-up. The results suggest that hot flashes and sleep disruptions are strongly correlated and that both acupuncture interventions resulted in a concomitant reduction in sleep disruptions.Implications for Clinical Practice:Nurses involved in holistic practice can recommend and/or provide the safe and effective alternative treatment of acupuncture for hot flash reduction and concomitant sleep disruptions. As a result, the quality of life for these women can be greatly improved.

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http://www.webmedcentral.com/article_view/1478

Special Features Of The Reaction Of Monoamine Contents Thymus And Lien`s Structure Of Rats For Acupuncture

The changes in the bioamine compound structures of the white rats thymus and spleen after acupuncture in 15 minutes, 1, 2 and 4 hours after acupuncture in acupuncture points GV 14 and LI 11 have been studied from the methods of the luminescent and immune histochemistry by usingfigures of the luminescent catecholamines and serotonine and also the serotonine index in ones capacity of criteria. The acupuncture has been carried out into the clinical effective acupuncture points LI 11 and GV 14. It was found in 15 minutes ten-minutes-acupuncture results in the increase of the content of the catecholamines and serotonine in the thymocytes of the cortical and brain substances and in the pre-medullar cells. After 4 hours of the experiment the level of the monoamine in the thymocytes of the brain substances and in subcapsular cells by degrees return to initial figures.

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http://www.webmedcentral.com/article_view/1285

Fibromyalgia And Vehicular Trauma: A Case Report

Fibromyalgia is a chronic condition characterized by widespread pain in muscles, tendons and ligaments of susceptible individuals. The patient may also experience a litany of other associated health conditions, such as, chronic fatigue and/or migraine headaches, to name a few.Fibromyalgia occurs in about 1 to 2 % of the population in the United States [1, 2] and women are more likely to develop the disorder than men.[1, 2]Fibromyalgia symptoms have been observed to begin after a physical or emotional trauma, but in many cases there appears to be no triggering event. [3] The diagnostic criteria and developing contributions to the scientific literature has increased considerably within a relatively short period of time.[4-6]The latent interest, in the author’s opinion, is probably due to the associated disability and the enormous economic affect the condition has on business and industry. Fibromyalgia was once ignored by a large segment of the traditional health care system and was generally dismissed and assumed to be the result of female hormonal imbalances or hysteria.[7-9] The prevailing attitudes in health care at that time made it difficult to provide care and/or manage this condition.[7] In 1990, the American College of Rheumatology set up criteria defining fibromyalgia as widespread pain of more than three months duration in combination with tenderness at 11 or more of 18 specific sites.[5]  Widespread pain is define as pain on the left and right side of the body; as well as, pain above and below the waist.[5]

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http://www.webmedcentral.com/article_view/1001