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A New Look at Safety With Hydroxychloroquine in COVID-19

While a precipitous drop in use may make it almost moot, new data show only 'modest' increases in QT prolongation and no arrhythmic deaths directly attributable to treatment. Medscape Medical News

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AHA Statement Highlights Cardiorenal Benefit of Diabetes Drugs

SGLT2 inhibitors and GLP-1 receptor agonists should be considered in people with type 2 diabetes and chronic kidney disease to protect against heart disease and kidney disease progression, the AHA says. Medscape Medical News

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FDA Advises Against Mercury Dental Fillings in High-Risk Groups

Pregnant or nursing women and young children are among those who should not receive fillings containing mercury, owing to the potential harmful effects of the release of mercury vapor over time. News Alerts

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Predicting Complications of Cytoreductive Nephrectomy in mRCC

Patients with higher intraoperative blood loss and those treated at lower-volume surgical centers had a greater risk of high-grade complications after undergoing CN for mRCC, according data analysis. Medscape Medical News

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DAPA-CKD Resets eGFR Floor for Safe SGLT2 Inhibitor Use

‘It's time to reduce the eGFR level for initiating an SGLT2 inhibitor to as low as 25,’ suggests an expert. Medscape Medical News

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VERTIS CV: Ertugliflozin Benefit Falls Short of Other SGLT2 Inhibitors

Analyses from the trial of the sodium-glucose transporter 2 inhibitor ertugliflozin in patients with type 2 diabetes helped better define positive effects the drug had on renal function. Medscape Medical News

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Uncontrolled CVD Risk Factors in Teens Flag Organ Damage

Adolescents with risk factors for cardiovascular disease (CVD) in the SHIP AHOY study were more likely to have signs of subclinical target organ damage in the heart and blood vessels. Medscape Medical News

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