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Preoperative F-18 fluorocholine PET/CT for the detection of hyperfunctioning parathyroid glands in patients with secondary or tertiary hyperparathyroidism: comparison with Tc-99m sestamibi scan and neck ultrasound

ConclusionsF-18 fluorocholine PET/CT shows superior accuracy over the conventional imaging modalities in patients with secondary or tertiary hyperparathyroidism. The combination of F-18 fluorocholine PET/CT and neck ultrasound may enable better surgical planning in these patients.Registration identification numberNCT04316845. (Source: Annals of Nuclear Medicine)

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https://medworm.com/791852416/preoperative-f-18-fluorocholine-petct-for-the-detection-of-hyperfunctioning-parathyroid-glands-in-p/

Physiological 18F-FDG uptake in the normal adult anal canal: evaluation by PET/CT

ConclusionsPET/CT scans occasionally showed high FDG uptake in the anal canal of healthy adults. Comparing the SUVmax values of liver FDG uptake may help differentiate between normal tissue and anal cancer. (Source: Annals of Nuclear Medicine)

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https://medworm.com/791546404/physiological-18f-fdg-uptake-in-the-normal-adult-anal-canal-evaluation-by-petct/

Effects of animal handling on striatal DAT availability in rats

ConclusionsIn conclusion, the SBR of striatum was increased after anesthesia by isoflurane and fasting. When designing an experiment using DAT imaging, the effects of isoflurane and fasting should be considered. (Source: Annals of Nuclear Medicine)

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https://medworm.com/791239743/effects-of-animal-handling-on-striatal-dat-availability-in-rats/

Does bone scintigraphy still have a role in the era of 68  Ga-PSMA PET/CT in prostate cancer?

ConclusionThis study has shown that 68  Ga-PSMA PET/CT overcomes the limitations of BS and proves superiority in detecting bone metastases, even in patients with SPECT/CT. Our findings present important implications that 68 Ga-PSMA PET/CT can replace BS in future practice. (Source: Annals of Nuclear Medicine)

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https://medworm.com/789413538/does-bone-scintigraphy-still-have-a-role-in-the-era-of-68-ga-psma-petct-in-prostate-cancer/

In vitro/in vivo assessment of the targeting ability of [ 99m Tc] Tc-labeled an aptide specific to the extra domain B of fibronectin (APT EDB ) for colorectal cancer

ConclusionsAlthough more studies are required to find out the full potential of this radio-ligand as an imaging probe, the present results nevertheless provide useful information about [99mTc] Tc-APTEDB, which might be beneficial in design and development of new [99mTc] Tc-APTEDB for efficient targeting of tumor in vivo. (Source: Annals of Nuclear Medicine)

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https://medworm.com/789108901/in-vitroin-vivo-assessment-of-the-targeting-ability-of-99m-tc-tc-labeled-an-aptide-specific-to-t/

Synthesis and evaluation of novel radioiodinated anthranilate derivatives for in vivo imaging of vascular endothelial growth factor receptor with single-photon emission computed tomography

Conclusion[125I]p-NPAM may have potential applications as a lead compound for future development of a clinically usable VEGFR imaging probe for SPECT. (Source: Annals of Nuclear Medicine)

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https://medworm.com/788652930/synthesis-and-evaluation-of-novel-radioiodinated-anthranilate-derivatives-for-in-vivo-imaging-of-vas/

Improvement in cognitive decline after indirect bypass surgery in adult moyamoya disease: implication of 15 O- gas positron emission tomography

ConclusionAdult patients with MMD might show improvement in their cognitive decline after successful indirect bypass surgery if they have a severely increased regional OEF before the surgery and an increased regional CMRO2 after the surgery.Clinical trial registrationURL:https://www.umin.ac.jp/ctr/. Unique identifier: UMIN000027949. (Source: Annals of Nuclear Medicine)

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https://medworm.com/788044664/improvement-in-cognitive-decline-after-indirect-bypass-surgery-in-adult-moyamoya-disease-implicatio/

Biodistribution and internal radiation dosimetry of a novel probe for thymidine phosphorylase imaging, [ 123 I]IIMU, in healthy volunteers

ConclusionIn this preliminary study, [123I]IIMU was safely administered to healthy adults, and its potential clinical use in TP imaging was revealed. (Source: Annals of Nuclear Medicine)

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https://medworm.com/786984745/biodistribution-and-internal-radiation-dosimetry-of-a-novel-probe-for-thymidine-phosphorylase-imagin/

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