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An impact of microscopic positive margin on incomplete response after I-131 treatment in differentiated thyroid cancer

ConclusionsMicroscopic positive margin was found to be significantly associated with incomplete response after I-131 therapy in patients with differentiated thyroid cancer after adjusting for tumor size, ETE, and cervical lymph node metastasis and also had a trend toward being associated with incomplete response after adjusting for pre-ablative Tg. (Source: Annals of Nuclear Medicine)

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Assessment of lung glucose uptake in patients with systemic lupus erythematosus pulmonary arterial hypertension: a quantitative FDG-PET imaging study

ConclusionsOur data indicated that increased lung FDG uptake in SLE-PAH patients correlates with SLE disease activity (SLEDAI) and immune/inflammatory status (C3 and C4). FDG-PET imaging may be developed as a potential intrapulmonary disease activity marker in SLE-PAH patients. (Source: Annals of Nuclear Medicine)

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AI approach of cycle-consistent generative adversarial networks to synthesize PET images to train computer-aided diagnosis algorithm for dementia

DiscussionOur results show that CycleGAN has the potential to generate a sufficient number of training images for CAD of dementia. (Source: Annals of Nuclear Medicine)

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A diagnostic strategy for Lewy body disease using DAT-SPECT, MIBG and Combined index

ConclusionIn the diagnosis of LBD, DAT-SPECT, MIBG myocardial scintigraphy, and Combined index may be reliable indices. In particular, MIBG myocardial scintigraphy was the specific modality for LBD diagnosis. Understanding the effectiveness and limits of DAT-SPECT and MIBG myocardial scintigraphy and using both properly will lead to a more accurate diagnosis and better treatment. (Source: Annals of Nuclear Medicine)

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Prognostic value of pretreatment tumor-to-blood standardized uptake ratio (SUR) in rectal cancer

ConclusionsIn our study, SUR was the only F-18 FDG PET/CT parameter found to be significant for PFS. The development of new parameters can increase the prognostic value of F-18 FDG PET/CT. (Source: Annals of Nuclear Medicine)

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Radiation exposure in nurses during care of 131 I-MIBG therapy for pediatric patients with high-risk neuroblastoma

ConclusionIndividual exposure to radiation was well controlled. Nurses who care for pediatric patients needing daily assistance must be aware of the radiation exposure risks, which can be reduced by establishing a care system and monitoring radiation exposure. (Source: Annals of Nuclear Medicine)

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Standardized thresholds of volume-based PET/CT parameters predicting survival of patients with pancreatic head cancer treated with stereotactic body radiation therapy

ConclusionsMTV (40%) was the optimal prognosticator among the relative thresholds of SUVmax for tumor delineation on PET/CT for LAPHC patients receiving SBRT. AD was also favorable indicators for OS and PFS of patients, and BED10 was more sensitive than AD in predicting the PFS of patients. (Source: Annals of Nuclear Medicine)

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Assessing the feasibility of NaF-PET/CT versus FDG-PET/CT to detect abdominal aortic calcification or inflammation in rheumatoid arthritis patients

ConclusionQuantitative assessment with NaF-PET/CT identifies increased molecular calcification in the wall of the abdominal aorta among patients with RA as compared with healthy controls, while quantitative assessment with FDG-PET/CT did not identify a difference in aortic vessel wall FDG uptake between the RA and healthy control groups. (Source: Annals of Nuclear Medicine)

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Retrospective correlation of 68 ga-psma uptake with clinical parameters in prostate cancer patients undergoing definitive radiotherapy

ConclusionsWe demonstrated a correlation between prostate tumor characteristics and PSMA tracer uptake. Patients with serum PSA  >  10 ng/mL, GS >  7, D’Amico high-risk group classification, and pelvic lymph node metastasis had significantly higher SUV than their counterparts. In addition, the primary tumor detection rate was higher in patients with serum PSA >  10 ng/mL and GS >  7. (Source: Annals of Nuclear Medicine)

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