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Poor cognitive performance predicts impairment in activities of daily living years later

Subtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete daily activities, such as managing medications or finances and other essential activities.

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Researchers uncover epigenetic drivers for Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes—how and when certain genes are turned on and off—in the brain. Results were published today in Nature Genetics.

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Noninvasive sleep test may help diagnose and predict dementia in older adults

Dementia is a growing problem for people as they age, but it often goes undiagnosed. Now investigators at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center have discovered and validated a marker of dementia that may help clinicians identify patients who have the condition or are at risk of developing it. The findings are published in JAMA Network Open.

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Research confirms link between sleep apnea and Alzheimer's disease

New research has confirmed long-suspected links between sleep apnea and Alzheimer's disease, finding identical signs of brain damage in both conditions.

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A genetic variant that protects against Alzheimer's disease promotes immune cell functions

A new study conducted by researchers at the University of Eastern Finland found that the PLCG2-P522R genetic variant, which protects against Alzheimer's disease, enhances several key functions of immune cells. The results obtained in the study highlight the importance of immune cells as a target of future development of new therapies for Alzheimer's disease.

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