Like presidential candidate Joe Biden, researcher Evan Usler has used his personal experience to help those with speech disorders. Usler studies motor speech and fluency disorders, including stuttering.
Aligning Science Across Parkinson's has announced a three-year, $7.2 million grant to scientists at UC San Diego and Germany to support research on LRKK2, a gene linked to Parkinson's disease. The new funding expands efforts using cryo-EM technology to produce previously unseen views of LRKK2.
For people with chronic insomnia, a good night's sleep is elusive. But what if insomnia symptoms could be alleviated by simply listening to one's own brainwaves? Researchers at Wake Forest Baptist Health conducted a clinical trial that showed reduced insomnia symptoms and improved autonomic nervous system function using a closed-loop, acoustic stimulation neurotechnology.
For the first time, scientists at UNC-Chapel Hill and Stanford solved the high-resolution structure of psychedelic drugs bound to the 5-HT2A serotonin receptor, a major step toward understanding how the drugs cause such wild effects and how they might be better used to treat psychiatric conditions.
A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders. The system, which uses extremely thin biomaterials implanted in the body, also protects nerve fibers (axons) that connect nerve cells in injured neural tissues, according to a study in the journal Advanced Materials.
While studied for nearly a century, little is known about how cavefish brains differ. A study is the first to look inside their brains with millimeter resolution to start to understand how the individual neurons and brain regions that drive complex behaviors, including sleep and feeding have evolved. This work has broad implications for the understanding of how brains evolve in many different animal models and is hoped to be widely used by the scientific community.
People with Parkinson's disease are more likely than people of a similar age without the disease to have a sudden drop in blood pressure upon standing, a phenomenon called orthostatic hypotension, according to a new study published in the September 16, 2020, online issue of Neurology(r), the medical journal of the American Academy of Neurology. The drop in blood pressure can lead to dizziness, lightheadedness, and even loss of consciousness and falls.
A genetic variation in some people may be associated with cognitive decline that can't be explained by deposits of two key proteins associated with Alzheimer's disease, amyloid β and tau, according to a study published in the September 16, 2020, online issue of Neurology(r), the medical journal of the American Academy of Neurology. The genetic variation leads to alterations in the metabolism of glutathione, an antioxidant, and may be associated with thinning of the cortex of the brain, the study says. The variation is found on the sixth chromosome.
Rush Medical College will be leading one of 21 teams receiving significant funding in hopes of making major advances in the fight against Parkinson's disease.